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NAC activates cystine-glutamate antiport transporters present in astrocytes, leading to the release of glutamate that stimulates extra-synaptic metabotropic receptors (mGluRs), thereby reducing the synaptic release of the neurotransmitter (Baker et al., 2002

In the present case where wide local excision was done, the healthy mucosal margin was considered to be approximately 3.0 cm, along with left segmental mandibulectomy and upper alveolectomy

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The two classes diverge with respect to atherothrombotic events: GLP-1RAs modestly reduce myocardial infarction in addition to stroke, whereas the SGLT2i MACE benefit is driven predominantly by reductions in cardiovascular death rather than myocardial infarction [5, 15]

The ability of these cells to evade treatment and drive metastasis makes them critical targets for improving cancer therapies