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Dehydration GLP-1 medications can cause dehydration through reduced fluid intake (you are simply drinking less) and increased fluid loss (particularly if GI side effects are present)

J Hematol Oncol 15:18 Jimenez JJ, DelCanto GM, Popovics P, Perez A, Vila Granda A, Vidaurre I, Cai RZ, Rick FG, Swords RT et al (2018) A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone-releasing hormone

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