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In such an abundance of glucose, insulin also stimulates the synthesis of glycogen by phosphorylation of glycogen synthase kinase 3 (GSK3), which leads to dephosphorylation and activation of glycogen synthase (McManus et al., 2005)

These functions make GLP-1 receptor agonists particularly valuable in managing type 2 diabetes by effectively lowering blood sugar levels and promoting weight loss, which is crucial for many diabetic patients

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J Biol Chem (1999) 274:1390814

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