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As per the analysis, researchers followed 333,687 US veterans with type 2 diabetes for three years, comparing 132,551 people prescribed GLP1s with 201,136 on sulfonylureas such as glipizide (Glucotrol), glimepiride (Amaryl) and glyburide (Diabeta and others)

Third, for TCM and other multimodal interventions, future studies should adopt hybrid trial designs that combine mechanistic endpoints with patient-centered outcomes

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Because they do not compete for the same metabolic resources, the risk of a toxic buildup is very low