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The first and most important for dietary histamine is Diamine Oxidase (DAO) an enzyme produced primarily in the intestinal mucosa (the lining of the small intestine) that metabolizes histamine in the gastrointestinal tract before it can be absorbed into the bloodstream

(More information) It is not yet clear whether supplementation with B vitamins, antioxidants, or omega-3 fatty acids protects against age-related cognitive decline

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