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doi: 10.1038/s41398-022-02297-y 112 KatzAAWainwrightSKellyMPAlbertPByrneR

MT-1 (Melanotan I, Afamelanotide, CAS 75921-69-6) is a synthetic linear tridecapeptide analog of -MSH with two targeted modifications Nle and D-Phe that enhance metabolic stability

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[9] [10] These coordinated actions help to regulate postprandial blood glucose levels effectively

Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase