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A., Yates, T., Khunti, K., & Davies, M

Each medications effectiveness can vary, but head-to-head data suggest that tirzepatide may be the most effective GLP-1 for weight loss to date

Key safety observations from available trial data include: Elevated resting heart rate in a dose-dependent manner Gastrointestinal adverse effects (nausea, vomiting, diarrhoea) as the most common side effects, consistent with the GLP-1 receptor agonist class [1] [3] No clinically significant QT interval prolongation was reported in available data, though the extent of formal thorough QT assessment has not been fully detailed in published sources