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Exercise induces radical production and the resultant exercise-induced oxidative stress in skeletal muscles impairs muscle force production and contributes to muscle fatigue during prolonged endurance exercise (Reid, 2008)

10.4103/0976-500X.119726 18 ChenW.FengJ.JiP.LiuY.WanH.ZhangJ

The daily rhythms of genes, cells and organs

Insufficient energy supplies lead to ineffective or limited neural functioning [98]

Similarly, the quantity of secreted factors, like cytokines and EVs collected from the flow-through, can be scarce for robust downstream analysis

10.1016/j.ejps.2018.01.046 95 PerteghellaS.RassuG.GaviniE.ObinuA.BariE.MandracchiaD.et al (2021)