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Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Glutathione is a tri-peptide composed of three amino acids and adding these amino acids to the diet does not guarantee elevated levels of Glutathione

, 67 , 113-121, Khomutov, M

Future investigations should prioritize formulation personalization for specific population groups and assess physiological outcomes through clinical validation

Hu F, Tu XF, Thakur K, Hu F, Li XL, Zhang YS, et al

However, the NAC monotherapy arm (600 mg three times daily) showed a trend toward slower decline in forced vital capacity (FVC) that did not reach statistical significance compared to placebo (Martinez et al., N Engl J Med, 2014) [45]