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Law et al

In addition to head pain, Migraines are typically accompanied by other symptoms: Auras floating over your vision Blurry or distorted vision Nausea and vomiting Sensitivity to light and sound Neck stiffness or pain A migraine can last for hours or even days, and its disruptive to the lives of those who suffer from them

fatigue/tiredness appears in the broader tolerability profile but was not the dominant safety signal compared with GI events

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never pour solutions down the sink, and place all sharps in an approved sharps container