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Journal of Medicinal Chemistry (2021) 7

In short, it's a protein that is normally digested once it reaches the stomach

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FIGURE 7 3.6 Silencing CA9 abolished the protective effect of ATT-I in DSS-induced colitic mice Using adenovirus-associated virus 9 (AAV9) to silence the CA9 gene, we investigated its critical role in the context of ATT-I-mediated suppression of ferroptosis and colitis