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However, as millions of people begin GLP-1 therapy, questions about less common side effectsincluding musculoskeletal painhave surfaced

These cells turn out to produce a number of IGFBPs under certain circumstances and it is known that this protein drastically lowers the impact of IGF-1 at its other receptors

Therefore molecules that inhibit the HGF/Met system can be expected to exhibit anti-cancer activity and attenuate malignant and metastatic transformations

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