While thirst itself isnt among the most frequently documented side effects, the gastrointestinal side effects that can lead to dehydration and subsequently trigger thirst are well-documented: Nausea: 12-24% of patients Diarrhoea: 12-22% of patients Vomiting: 2-13% of patients These digestive effects can cause fluid loss and trigger compensatory thirst, making it a secondary effect of the medications primary side effects
Paired (in group) and unpaired (between groups) Student t -test were used in microCT analysis
Some feel a slight decrease in hunger
The dosage must be taken once daily in the fasted state with minimal liquid and at a substantially higher dose than the approved once-weekly injectable formulation ( 12, 13 )
Clinical assessment includes diagnostic imaging, serum testing, possible biopsy analysis and consultation with a nephrologist to reduce the risk for irreversible damage to the renal system and to rule out other potential causes of kidney injury
Avoid excessive amounts, which can increase irritation risk
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