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doi: 10.1093/ajcn/nqac193 137 Al-SaffarNMTroyHRamirez de MolinaAJacksonLEMadhuBGriffithsJRet al
If weight reduction is a central goal, discuss alternatives rather than changing doses or combining GLP-1 medicines on your own
Conclusions Despite the medical complexity and the later disease stage, patients with T2DM in this study experienced significant reductions in HbA1c within 6 months following initiation of oral semaglutide
In another randomized controlled trial assessing the effect of hops extract on satiety in healthy-weight men, the treatment also led to a significant reduction in food intake, stimulated prelunch ghrelin, postprandial cholecystokinin, glucagon-like peptide 1, and peptide YY secretion compared to placebo (these neuropeptides promote fullness and reduce food intake) [2]
Additionally, increased plasma insulin, decreased triglycerides, and improved myocardial glucose uptake were observed in the GLP-1 treated group [74]
