Given the multifactorial nature of glaucoma-associated ocular surface disease (G-OSD)which involves chronic inflammation, oxidative stress, and tear film instabilitydeveloping novel therapies that target these intersecting pathways is of considerable clinical relevance
However, implementing such approaches requires careful evaluation of evidence quality and vigilant monitoring for herbdrug interactions
First and foremost, individuals should consult with a healthcare professional, particularly if they have pre-existing medical conditions or are taking other medications
It accomplishes this through reduction of the NF-B signaling pathway
NAC, an antioxidant, blocks high glucose (HG)-induced ferroptosis by enhancing mitochondrial GSH activity and upregulating GPX4 expression
USA 106 , 2197221977 (2009)