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Niacin (B3) ASA modulating prostaglandins to reduce niacin-flush

T2DM is often accompanied with islet fibrosis in both animal models and patients [4, 5]

However, it has been observed in clinical trials

The AMPK signaling pathway plays a core role in the regulation of energy metabolism, lipid metabolism, inflammation, and autophagy and has become an important target for the prevention and treatment of NAFLD