Gastrointestinal side effects including nausea and vomiting have been reported with both exenatide and liraglutide treatment although these side effects are often transient and occur mainly during the first few weeks of treatment in the dose escalation phase
Clinical trial data from Eli Lillys Phase 2 study showed that the 12mg weekly dose produced an average weight loss of 24.2% over 48 weeks, with over 80% of participants losing at least 15% of their starting body weight
Findings Suggest Drug Has the Potential To Reduce the Risk of Heart Disease, Diabetes, and Stroke In adults with obesity or overweight, weekly treatment with the glucagon-like peptide 1 (GLP1) receptor agonist semaglutide leads to reduced excess body fat and increased lean body mass, according to an industry-sponsored study presented virtually at ENDO 2021, the Endocrine Societys annual meeting
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Maybe part of a broader clinical picture your doctor has been missing or hasn't even considered yet, and GLP ones may aid in this