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The insulinotropic effects of GLP-1 are regulated by glucose levels and do not disrupt the glucagon-mediated counter-regulatory mechanism during hypoglycemia [13], making GLP-1/GLP-1R axis a highly suitable target for incretin-based treatments aimed at controlling diabetic hyperglycemia

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The pharmacokinetic profile of liraglutide injection in the pediatric patients was consistent with that in adults

LAG-2 ligand from DTC niche activates proteolytic cleavage of GLP-1 receptor in germline stem cells