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Retatrutide is a triple GLP-1/GIP/glucagon receptor agonist that showed up to 24.2% weight loss in phase 2 trials at 48 weeks, potentially exceeding both CagriSema and tirzepatide
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The peptide's cognitive enhancement mechanism operates through hepatocyte growth factor (HGF) pathway potentiation, which is distinct from traditional nootropic mechanisms and represents a novel approach to cognitive enhancement research focused on structural brain plasticity
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