As the science of nutrition continues to evolve, it seems the trend is going back to basics
Employers are seeing impact on loss ratios
Abbreviation PI Paralytic ileus T2D Type 2 diabetes GLP-1RAs Glucagon-like peptide-1 receptor agonists MR Mendelian randomization GWAS Genome-wide association studies SGLT-2 Sodium-glucose cotransporter-2 HbA1c hemoglobin A1C GTEx Genotype-Tissue Expression IVW Inverse-variance weighted GRCh37 Genome Reference Consortium Human Build 37 Chr Chromosome EA Effect Allele NEA Non-Effect Allele NES Normalized Effect Size SE Standard Error OR Odds ratio LD Linkage Disequilibrium Footnotes Declarations The authors declare that they have no conflict of interest
Large real-world UK CPRD cohort suggesting lower cardiovascular and serious kidney event rates with combination therapy
British Journal of Psychiatry 167, 99103.CrossRefGoogle ScholarPubMed Suchankova, P, Yan, J, Schwandt, ML, Stangl, BL, Caparelli, EC, Momenan, R, Jerlhag, E, Engel, JA, Hodgkinson, CA, Egli, M and Lopez, MF (2015) The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence
A consensus report by the American Diabetes Association (ADA) and the European Association for the study of Diabetes (EASD)