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Addiction, 104: 1085-1099

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Fasting or poor nutritional support during a detoxification program may have many adverse health effects, including: Decreased energy production Brain fog Mood and sleep difficulties Breakdown of lean tissue Up-regulation of detox Phase I enzyme activities with a concomitant increase in oxidative stress Decreased levels of Phase II co-factors The majority of toxins are lipid-soluble molecules

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these are vital for hormone production and receptor sensitivity