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10.1159/000502149 Neuropsychobiology 151 SinghA.VarmaM.RaiM.Pratap SinghS.BansodG.LauxP.et al (2024)

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(PubMed) Capelli I, Cianciolo G, Gasperoni L, et al

Second, patients with chronic kidney disease (CKD) stages 3b through 5 may have impaired copper excretion through bile and urine [13]

The suggestion is that reduced GR activity and therefore less 'reduced glutathione' may be implicated in Irritable Bowel Syndrome - possibly because it has less defenses against free radicals, the cause of oxidative stress

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