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[DOI] [PubMed] [Google Scholar] 63.Krishna R, Gumbiner B, Stevens C, et al

References Mechanism of Action 1 The activity of GHK-Cu is thought to be multifaceted and includes: GHK-Cu has been associated with the upregulation of genes involved in tissue repair, anti-inflammatory signaling, and antioxidant defense, and the downregulation of genes linked to fibrosis and oxidative stress

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This method is common in animal models to study systemic or localized but deeper tissue effects