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Importantly, the largest reductions in BMI were observed in the southern United States, which also reported the highest rates of GLP-1 RA dispensing claims (Rader et al., 2024), a geographic concordance that is consistent with a causal contribution of these pharmacotherapies to the observed population-level BMI decline

An observational cohort study analyzed 6 cases of functioning lactotroph tumors treated with ICI and a favorable response was observed in two patients (partial response and stable disease), whereas the other 4 underwent a further increase in prolactin levels and radiological progression of the disease (85)

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declares funding to conduct clinical trials from AstraZeneca, Bayer, Boehringer Ingelheim and Novo Nordisk (all to the INCLIVA Research Institute)