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The NHS Eatwell Guide recommends that starchy carbohydrates should comprise approximately one-third of food intake for the general population, with emphasis on higher-fibre varieties

GLP-1 is a target for treatment of diabetes because of the primary peripheral functions of inducing insulin secretion from pancreatic cells, gut emptying and inhibiting glucagon secretion which results in lower blood glucose levels ( GLP-1 can also be produced by neurons in central nervous system (CNS) ( Pathogenesis of AD Amyloid plaque Amyloid beta (A) is a peptide with a molecular weight of 4 KDa and a length of 40-42 amino acids ( 2+ channels and AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors, to which the neurotransmitter glutamate binds, so A is the most neurotoxic form ( Neurofibrillary tangles Tau is a microtubule-associated protein and mainly found in the axonal compartment ( Synaptic dysfunction and neurotransmitter imbalance It has been well established that cholinergic transmission is essential for memory, learning, attention, and other higher brain functions, so cholinergic deficits play a key role in the neuropathology of AD ( Neuroinflammation Neuroinflammation, microglia activation in response to amyloid deposition, plays a central role in the pathogenesis of AD ( Insulin resistance For the past few years, AD has also been considered as type 3 diabetes because of insulin resistance (IR) and dysregulation of insulin signaling in the brain ( is mainly transported across the BBB

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Spice It Up With Fermented Foods Fermented foods like: Kimchi Sauerkraut Kefir ...support a diverse gut microbiome, which plays a key role in GLP-1 response and insulin sensitivity

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For patients who cannot tolerate GLP-1 side effects, who have already lost weight with GLP-1 therapy and want to sustain metabolic health, or whose primary issue is insulin resistance and visceral fat rather than caloric surplus, MOTS-c addresses a different problem