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Commun Biol 3 , 9 (2020)

21,22 Another suggested hypothesis is that ethanol may directly enhance the activity of NAD(P)H:quinone reductase, serving to reconvert quinone metabolites back to native APAP and thereby limiting the accumulation of toxic metabolites

Sertraline's effect on weight is variablesome patients experience weight loss initially, whilst others may gain weight with long-term use

Most resolved during the titration phase as the body adapted

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+ - Early Effects: Many patients notice initial changes-such as increased energy levels or a decrease in appetite-within the first 12 weeks of consistent use