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Comprehensive analysis of adverse events associated with SGLT2is: a meta-analysis involving nine large randomized trials

Its use for weight loss is a more recent application, with brand names like Wegovy, Saxenda, and Zepbound dominating markets in the current health landscape

Hypothyroidism has also been associated with insulin resistance and risk of type 2 diabetes

Qiao Q, Ouwens MJ, Grandy S, Johnsson K, Kostev K

Vet Comp Oncol

This exceptional clinical aggression is consistent with the tumors high proliferative index (Ki-67 50%) and the R2 resection status, suggesting early dissemination of gross or microscopic residual disease along the neuraxis, potentially via perineural spread or CSF-mediated seeding