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Canagliflozin reduced the risk of the primary composite outcome (ESKD, doubling of serum creatinine, or renal or cardiovascular death) by 30% compared to placebo, with consistent effects across all prespecified subgroups [46]

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311, R200R208.CrossRefGoogle ScholarPubMed Boehmer, BH, Brown, LD, Wesolowski, SR, Hay, WW, Rozance, PJ

Lab testing to check for MTHFR mutations used to be costly and required a prescription and a blood draw

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