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To address the problem of once-a-day injections of Liraglutide, Lilly launched Dulaglutide, which is administered once a week and was approved by the FDA in 2014 for the treatment of type 2 diabetes

Tirzepatide (weekly) is a dual GIP/GLP-1 agonist with potentially greater results

Retatrutides added glucagon may offer enhanced metabolic effects, but those benefits are still being studied

1ip and Extended Data Fig

Quick Answer: No, commercially available GLP-1 patches have not been proven effective and lack FDA approval for weight loss or diabetes management

Butler J, Shah SJ, Petrie MC et al (2024) Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials