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The one human trial that will measure tolerability directly has not started reporting it is only recruiting (planned 2026), studies a topical gel on small standardized wounds , and lists safety as a secondary, not primary, outcome (NCT07437586)

10.1073/pnas.0511020103 Proc

Li L, Li B, Zhang M

After the pain decreases, your doctor may recommend rehabilitation exercises to strengthen surrounding muscles and help restore as much movement and function as possible