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Statements Author contributions EJ conducted the literature search, summarized these data, and drafted the review

Pettus emphasized

Carotid scans to assess plaque burden were conducted at baseline and study exit

Published research on grape seed extract has examined its antioxidant properties and potential effects on vascular health and oxidative stress reduction

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Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGF1-mediated tumor progression