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ghk-cu tolerance or desensitization or loss of effectiveness or downregulation

ghk-cu tolerance or desensitization or loss of effectiveness or downregulation peptide long-term use as a multifunctional copper peptide: synthesis routes, process engineering and emerging applications ghk cu tolerance desensitization – ghk-cu tolerance desensitization loss of

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Description

To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets

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