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Notably, conflicting findings have been reported regarding the abundance of certain bacterial taxa (e.g., Megasphaera and Barnesiella ), potentially due to population heterogeneity, methodological variability, or confounding factors such as constipation and allergies (De Sales-Milln et al., 2024

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These interdisciplinary approaches are expected to reveal novel biomarkers that can predict cellular senescence and the aging trajectory, as well as therapeutic targets for interventions aimed at reversing senescence in tissues

93,94,95,96 Dysfunctional lysosomes and genetic variants such as IRGM further exacerbate disease progression

Note: This is a health supplement and should be used along with a balanced diet and regular exercise