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Weight management: It helps with weight management by increasing fat burning and reducing fat storage

Real-world evidence for GLP-1 medications

There are no approved therapies for youth that have demonstrated a clinically meaningful impact on body weight or BMI reduction compared with placebo. Hannon said the 2025 American Diabetes Association Standards of Care currently recommend GLP-1 therapy if children and adolescents with type 2 diabetes are unable to achieve an HbA1c of 6.5% or less with metformin or insulin therapy

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Zhong, M

Phase 2 trial data showed substantial body weight reductions with retatrutide, making indirect anti-inflammatory effects biologically plausible