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Several meta-analyses found a link between resveratrol consumption and improvement of FMD, serum vascular adhesion molecules (ICAM-1), SBP, TC, fasting glucose, HbA1c, AST and ALT (Reference Abdelhaleem, Brakat and Adayel56Reference Soltani, Sharifi-Zahabi and Sangsefidi60)
It remains unclear whether any changes in PK translate to an increased propensity to toxicity with no studies demonstrating this conclusively
[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Shaker E, Mahmoud H, Mnaa S
Aroda VR, Rosenstock J, Terauchi Y et al (2019) PIONEER 1: randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes
College Cardiol
Underestimation of risk : Conversely, they may underestimate the risk in some individuals taking GLP-1s, where varied responses to treatment may lead to diverging outcomes
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