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Tirzepatide, by contrast, showed no significant increase in biliary risk in the available data

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Remember, natural alternatives are not pharmacologically equivalent to semaglutide, and they may not show the same effects

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The ASCO GI 2026 data suggest that GLP-1 therapy may be particularly relevant for metabolically high-risk populations, including individuals with obesity, insulin resistance, or type 2 diabetesgroups that now account for a substantial proportion of colorectal cancer burden