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Ashwagandha is traditionally associated with a calming and relaxing effect

Other drugs are either too hydrophilic (eg, atenolol) or too lipophilic (eg, acyclovir) to be absorbed easily, and their low bioavailability is also due to incomplete absorption

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Reproducibility of the circadian rhythms of serum cortisol and melatonin in healthy subjects: a study of three different 24-h cycles over six weeks