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Cleveland Clinic explains that starting out with too large of a calorie deficit can lead to side effects like fatigue, headaches, dehydration, nausea and irritability. If you also cut too much protein from your diet, your body may begin breaking down muscle for fuel, which can further impact strength and metabolism. Sleep plays a role too
"What we really should be doing is supporting nutrition for people throughout their weight loss journey," Jacques said
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Even with orally administered GLP-1 pills, roughly half of patients don't take their medications as prescribed
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