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Advances in patented CB1 receptor antagonists for obesity

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Cancer cells are known to be sensitive to ferroptosis, giving a possible way around therapy resistance [86]

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MC4R in particular has been the focus of extensive research into its role in hypothalamic appetite circuits, sympathetic tone, and downstream neuroendocrine signalling making MT-2 a key pharmacological tool in these research areas

Dysbiosis can compromise BBB structure through inflammatory cytokine release, harmful microbial metabolites, and reduced production of protective SCFAs