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Zhu T et al (2015) Glucagon like peptide-1 (GLP-1) modulates OVA-induced airway inflammation and mucus secretion involving a protein kinase A (PKA)-dependent nuclear factor-B (NF-B) signaling pathway in mice

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[32] found that exendin-4 mitigated resistance to the androgen receptor inhibitor enzalutamide in prostate cancer via the PI3K/AKT/mTOR pathway, suggesting that a combination of exendin-4 with enzalutamide may be a more effective therapeutic option for advanced prostate cancer

Delayed approach: Add muscle preservation peptides after several months when muscle loss becomes apparent on body composition testing

Collect the viral supernatant, mix with the supernatant collected by 48 h

The mean age of the trial population was 10 years