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In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial
This can be especially important because fluctuations in energy levels can make MS-related fatigue worse
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This conclusion is based on the findings from a six-month randomized, double-blinded, placebo-controlled trial involving 54 non-smoking adults who were assigned to receive either a placebo, 250 mg/day of GSH, or 1000 mg/day of GSH
Zhang, G., et al