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When combined with alpha-lipoic acid, some early research has shown that benfotiamine may enhance effects in reducing pain and improving nerve conduction in people with diabetic neuropathy.8 The synergy likely stems from their complementary mechanisms: benfotiamine helps manage glucose-induced damage, while ALA reduces oxidative stress and improves blood flow

However, its important to consult with a healthcare professional to determine the optimal dosage tailored to your specific needs

"If we can reduce the mast cell problem, we can facilitate taking other drugs to treat ME/CFS," she said

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Its influence on melanin production makes it relevant in skin-focused research