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This shift is partly due to the loss of oestrogen's protective effects against fat accumulation in the abdominal area

the pairing is the canonical GHRH + GHRP combination referenced across growth-hormone-secretagogue research literature

Interestingly, at least Yasuda and colleagues also saw a significant reduced food intake in the KO rats irrespective of the diet (45), which might be due to changed receptor specificity of neuropeptide Y (NPY), which was shown to be more potent in KO rats to influence food intake and feeding motivation (49)

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