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They must be verified through analytical testing

In addition, during vaso-occlusive episodes, SCD patients show distinct metabolite profiles from those at steady-state 7,8,9,10

Nadeau recommends adopting a positive mindset

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Gamma-glutamyltransferase as a risk factor for cardiovascular disease mortality: an epidemiological investigation in a cohort of 163,944 Austrian adults

In addition, the role of other abnormalities in the folate pathway beside FR autoantibodies, such as genetic polymorphisms, in treatment response needs to be investigated