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HUBERMAN: As a consequence, all of the things that growth hormone does like encouraging higher metabolism, fat loss, the growth of muscle tissue, et cetera, is dramatically reduced as we go from 30 to 40 to 50 and on and on

Only eight FDA-approved facilities worldwide can produce GLP-1 peptides at scale, so any disruption, such as the 2024 fire at a Danish supplier, quickly triggers global shortages

The subsequent FDA approvals of Wegovy and Zepbound for weight management further solidified what had already become common prescribing behavior across various medical specialties

1 CVS says the change is intended to improve affordability and expand treatment options for employers offering GLP-1 coverage

That spending with that deterioration in confidence