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Moreover, HGF cooperates with nerve growth factor (NGF) in vitro to enhance the axonal growth of dorsal root ganglion sensory neurons (Maina et al., 1997) and sympathetic neurons (Maina et al., 1998)

By inhibiting NNMT, 5-Amino-1MQ reduces 1-MNA formation and alleviates the methyl sink, increasing SAM availability for other methylation reactions, while freeing nicotinamide for recycling through NAMPT toward NAD

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10.1172/JCI72151 [DOI] [PMC free article] [PubMed] [Google Scholar] 39.Michell-Robinson MA, Moore CS, Healy LM, Osso LA, Zorko N, Grouza V, et al

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2018, doi:10.3390/molecules23030575 Derosa, Giuseppe et al