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Blood Glucose and HbA1c Blood Glucose and HbA1c Studies in people with type 2 diabetes have reported reductions in HbA1c and body weight

It's worth noting that sugar-free confectionery containing polyols (such as sorbitol or xylitol) may worsen GI symptoms in some people taking GLP-1 medications, so these should be introduced cautiously

Research has identified several variants with documented relationships to GLP-1 pathway function and metabolic response, including TCF7L2 (incretin sensitivity), MC4R (hypothalamic satiety signaling), FTO (metabolic set point and satiety baseline), LEPR (leptin receptor sensitivity), and ADIPOQ (adiponectin secretion and insulin sensitivity)