select trial semaglutide cardiovascular outcomes without diabetes 2023 A Skeptical Take of for Cardiac Protection From diabetes drugs... to weight

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4 The two medications work on different aspects of cardiovascular risk

La clave del xito radica en dos cosas: la personalizacin del tratamiento y la experiencia del especialista que lo aplica

Treatment of hypertension is indicated in virtually all older adults, and lipid-lowering and aspirin therapy may benefit those with life expectancy at least equal to the time frame of primary or secondary prevention trials

These medications reduce hyperglycemia (Hb1Ac reduction of 0.8 1.4%) through the inhibition of glucose reabsorption in the proximal convoluted tubule of the kidney and the resulting increase in glycosuria ( In light of this evidence, these therapies have opened a new paradigm not only for the management of altered glucose metabolism in T2D but also in consideration of their pleiotropic effects ( Emerging data indicate that the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis may play a role in either mediating the metabolic and neuroendocrine effect of these drugs or responding to the profound body modifications fostered by GLP-1RAs and SGLT-2is

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