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For patients needing to lose a large amount of weight for immediate health risks, surgery is also an option

The control of food-related glucose spikes along with a reduction in food intake due to inhibition of gastric emptying led to the approval of GLP-1 RAs for the treatment of diabetes and obesity [2,3]

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Apart from neglect of still-effective non-pharmacological approaches, access to GLP-1 agonist therapy will remain a large question, particularly given existing costs and globally constrained supply

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AOD-9604 (Advanced Obesity Drug 9604) addresses this challenge through remarkable selectivity