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The amount of a given agent that will correspond to such an amount will vary depending upon factors such as the particular compound, disease condition and its severity, but is nevertheless routinely determined in a manner known in the art according to the particular circumstances surrounding the case, including, e.g., the specific agent being administered, the route of administration, the condition being treated, and the subject or host being treated
134 established a link between the increased expression, and changes in the localisation, of SOP enzymes and suppression of the growth-restricting effects of excess H 2 S in colorectal carcinoma cells
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